Christoph Rieck
Dr. Christoph Rieck
Christoph, a deaf-born, studied Biology (Dipl. Biol.) in Erlangen at FAU and in Kiel at CAU. In 2002, he finished his PhD with the topic „Biosynthesis of very long chain fatty acid synthesis in yeast (Saccharomyces cerevisiae)“ at the chair of Biochemistry, Prof. Eckhart Schweizer, at the FAU. Thereafter, Christoph worked as Post Doc at the chair of Biochemistry of Prof. Uwe Sonnewald at the FAU in the group of Frederik Börnke. In 2008, he started his career as “Akademischer Rat” at the FAU at the Chair of Pharmaceutical Biology of Prof. Wolfgang Kreis and studied the pathways of cardenolide biosynthesis in Digitalis ssp. plants and transformation of those pathways in yeast cells, generating artificial cells in a synthetic biology 2.0 manner. 2016 he received his appointment as “Akademischer Oberrat”; since 2021, Christoph is safety and administrative officer at the Chair of Pharmaceutical Biology.
Publications
2021
21-Hydroxypregnane 21-O-malonylation, a crucial step in cardenolide biosynthesis, can be achieved by substrate-promiscuous BAHD-type phenolic glucoside malonyltransferases from Arabidopsis thaliana and homolog proteins from Digitalis lanata
In: Phytochemistry 187 (2021), Art.Nr.: 112710
ISSN: 0031-9422
DOI: 10.1016/j.phytochem.2021.112710 , , , , , , , , , :
2019
Biosynthetic approach to combine the first steps of cardenolide formation in Saccharomyces cerevisiae
In: MicrobiologyOpen (2019), Art.Nr.: e925
ISSN: 2045-8827
DOI: 10.1002/mbo3.925 , , , , , , , :
2021
21-Hydroxypregnane 21-O-malonylation, a crucial step in cardenolide biosynthesis, can be achieved by substrate-promiscuous BAHD-type phenolic glucoside malonyltransferases from Arabidopsis thaliana and homolog proteins from Digitalis lanata
In: Phytochemistry 187 (2021), Art.Nr.: 112710
ISSN: 0031-9422
DOI: 10.1016/j.phytochem.2021.112710 , , , , , , , , , :
2019
Biosynthetic approach to combine the first steps of cardenolide formation in Saccharomyces cerevisiae
In: MicrobiologyOpen (2019), Art.Nr.: e925
ISSN: 2045-8827
DOI: 10.1002/mbo3.925 , , , , , , , :
2003
Rössler H, Rieck C, Delong T, Hoja U, Schweizer E
Functional differentiation and selective inactivation of multiple Saccharomyces cerevisiae genes involved in very-long-chain fatty acid synthesis.
In: Mol Genet Genomics 269(2): 290 – 8
DOI: 10.1007/s00438-003-0836-0
2002
Rössler H, Rieck C, Schweizer E
YBR159p-encoded β-ketoacyl reductase is involved in one of three different yeast fatty acid elongation systems.
In: Chemistry and Physics of Lipids 118 (2002): 34